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The Golgi Network, Volume II - Akihiko Nakano & Jaakko Saraste.pdf

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Description & Overview

The second volume (of two) of The Golgi Network book, explores the role of this organelle in a plethora of cellular functions, complementing perfectly the first volume with the most recent discoveries.

In this part, the description of the machinery involved in trafficking explores the interaction of Golgi with different organelles such as ER and the vesicular system, as well as protein complexes in charge to execute these tasks, like COG, and GARP, among others. An important part of this volume studies in depth the sorting mechanisms that occur in different areas of the cell and their most important components, a part of this volume includes the effects of Golgi on glycosylation systems, and in a special section, we can learn about new Golgi-associated functions such as the nucleation of microtubules and their effect on signaling in the immune system.

The last part of this volume explores the association of Golgi and its malfunction with different diseases, focusing mainly on cancer and neurodegeneration.

In this fashion, this volume is a valuable resource for professionals working on different fields of Golgi research and is strongly suggested to those involved in translational science.
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