This book presents recent research and practice advances in the field of Service Science. It contains selected papers from the 2025 INFORMS International Conference on Service Science, held in Oxford, UK from July 1-3, 2025. The book explores how AI, data, and digital technologies are driving sustainable transformation across industries and society at both national and international levels. It presents new theoretical frameworks, empirical research, and practical applications in the interdisciplinary fields of AI, digital transformation, and service science. The content includes empirical studies, modeling, and theoretical research that examine how AI and data are advancing sustainability across service systems. Topics covered include AI-driven smart cities, sustainable systems, the digital economy, AI ethics and governance, public health and AI, human-AI collaboration, machine learning and data-driven decision-making, quantum computing in service science, and the digital transformation of traditional industries.