You are staring at a dot plot at 2 a.m., and the CD markers do not add up to a clean answer. Every hematopathology fellow and medical laboratory scientist hits this wall: the textbook explains the theory, but not how to read the actual scatter when three antigen populations overlap.

This 2026 edition closes that gap. Across 25 chapters we walk through instrument fluidics, compensation, panel design, and the full WHO-based diagnostic algorithm for acute leukemia, myelodysplastic syndrome, and every major B-cell, T-cell, and plasma cell neoplasm you will encounter on the bench.

Without this framework, gating errors and missed aberrant markers cost hours of rework and can delay a diagnosis that a patient is waiting on.

With it, you gain:

• Step-by-step gating strategies for normal maturation versus neoplastic immunophenotypes

• WHO classification criteria mapped directly to marker panels for AML, ALL, CLL, lymphoma, and myeloma

• Minimal residual disease monitoring protocols used in real reference laboratories

• Over 45 detailed clinical illustrations showing exact gating hierarchies, marker color schemes, and labeled scatter plots

• A QR-linked video course with more than 100 curated tutorial videos covering instrumentation, panel troubleshooting, and case-based interpretation

Written by a practicing hematopathologist, this reference reads like a mentor at your shoulder, not a dense manual you shelve after one read.

Scan the QR code on the final page to unlock the full video course and keep learning past the last chapter.