This book presents cutting-edge papers and perspectives on virtual rehabilitation and tele-rehabilitation. The book covers themes ranging from pediatrics to older adults, addressing rehabilitation of gait and mobility, upper limb movement and cognition. The articles in this book have been presented at the 2025 World Conference of the International Society for Virtual Rehabilitation (WCISVR 2025) during RehabWeek 2025. Researchers, clinicians, industry and policy makers, as well as graduate students who are interested in virtual rehabilitation will find this book a great reference and a useful learning resource.