This book presents innovative and sustainable solutions to one of the most urgent challenges in animal agriculture, the rise of antibiotic resistance. It addresses global concerns over the misuse of antibiotics and the consequences for food safety, public health, and environmental responsibility. Designed as a timely resource for researchers, veterinarians, feed formulators, and policymakers, it delivers a clear and structured overview of natural and novel strategies that support animal health and productivity. Readers will find detailed explanations of phytogenic feed additives such as herbs, spices, and essential oils, along with probiotics, prebiotics, organic acids, and enzymes that support gut health and help prevent infections. The book also examines bacteriophages, advanced vaccination methods, and other emerging approaches with attention to both mechanisms and practical use. Its unique strength lies in the integration of recent research with real‑world case studies from a wide range of livestock systems. Readers gain a balanced understanding of the benefits, limitations, and economic considerations of green alternatives, and this understanding supports informed decisions that align with long‑term sustainability goals. As demand for antibiotic‑free animal products grows, this book fills a critical need in the field and guides ethical and productive livestock management.